[Measurement of antimicrobial consumption using DDD per 100 bed-days versus DDD per 100 discharges after the implementation of an antimicrobial stewardship program]. / Evaluación del consumo de antimicrobianos mediante DDD/100 estancias versus DDD/100 altas en la implantación de un Programa de Optimización del Uso de Antimicrobianos.

INTRODUCTION: Monitoring antimicrobial consumption in hospitals is a necessary measure. The indicators commonly employed do not clearly reflect the antibiotic selection pressure. The objective of this study is to evaluate two different methods that analyze antimicrobial consumption based on DDD, per stay and per discharge, before and after the implementation an antimicrobial stewardship program. MATERIAL AND METHODS: Comparative pre-post study of antimicrobial consumption with the implementation of an antimicrobial stewardship program using DDD per 100 bed-days and DDD per 100 discharges as indicators. RESULTS: Hospital bed days remained stable and discharges increased slightly along the period of study Antibiotic consumption in DDD per 100 bed-days decreased by 2.5% versus 3.8% when expressed as DDD per 100 discharges. Antifungal consumption decreased by more than 50%. CONCLUSIONS: When average hospital stay decreases, reductions in the consumption of antimicrobials with an antimicrobial stewardship program system occur at the expense of reducing the number of patients receiving treatment, while increases occur due to longer durations of treatment.

Evaluación del consumo de antimicrobianos mediante DDD/100 estancias versus DDD/100 altas en la implantación de un Programa de Optimización del Uso de Antimicrobianos / Measurement of antimicrobial consumption using DDD per 100 bed-days versus DDD per 100 discharges after the implementation of an antimicrobial stewardship program

Introducción. La monitorización del consumo de antimicrobianos en los hospitales es una medida necesaria. Los indicadores habituales no reflejan claramente la presión del antimicrobiano sobre el paciente. El objetivo es evaluar dos métodos de consumo basados en las DDD, por estancia y por alta, antes y después de un Programa de Optimización de Antimicrobianos (PROA). Material y métodos. Estudio comparativo del consumo de antimicrobianos en seguimiento por un PROA utilizando las DDD/100 estancias y altas. Resultados. Las estancias se mantuvieron estables y las altas incrementaron ligeramente. El consumo de los antibacterianos disminuyó por estancias y por altas: 2,5% versus 3,8%. El consumo de antifúngicos disminuyó más del 50%. Conclusiones. En un contexto de reducción de estancia media, la disminución del consumo de antimicrobianos en seguimiento por un PROA se produce a expensas de disminuir los pacientes en tratamiento, mientras que aquellos que se incrementan se producen a expensas de una mayor duración (AU)

Introduction. Monitoring antimicrobial consumption in hospitals is a necessary measure. The indicators commonly employed do not clearly reflect the antibiotic selection pressure. The objective of this study is to evaluate two different methods that analyze antimicrobial consumption based on DDD, per stay and per discharge, before and after the implementation an antimicrobial stewardship program. Material and methods. Comparative pre-post study of antimicrobial consumption with the implementation of an antimicrobial stewardship program using DDD per 100 bed-days and DDD per 100 discharges as indicators. Results. Hospital bed days remained stable and discharges increased slightly along the period of study Antibiotic consumption in DDD per 100 bed-days decreased by 2.5% versus 3.8% when expressed as DDD per 100 discharges. Antifungal consumption decreased by more than 50%. Conclusions. When average hospital stay decreases, reductions in the consumption of antimicrobials with an antimicrobial stewardship program system occur at the expense of reducing the number of patients receiving treatment, while increases occur due to longer durations of treatment (AU)